Drug half-life
The time required for the concentration of a drug in the plasma to reduce by 50% through metabolism and excretion. A fundamental metric in pharmacokinetics.
Key Parameters
- Governs dosing interval and the time required to reach steady state.
- Dependent on clearance and volume of distribution.
Observations
- 2026 04 14 Malaria vaccination via mosquitos: In malaria vaccination models using mosquitoes, animals can achieve lifelong protection from reinfection despite the drug having a very short half-life.
2026 04 14 Malaria vaccination via mosquitos
Source Notes
- 2026-04-14: The Starlink Breakthrough Everyone Missed